Magnetoelastic biosensors are a type of biosensor that detects and quantifies biological molecules such as DNA, proteins, and viruses using magnetoelastic materials. These biosensors are based on the magnetostriction concept, which describes the capacity of some materials to alter form or size in response to an applied magnetic field.
In a magnetoelastic biosensor, a magnetoelastic material, such as iron or nickel, is coated with a biological recognition element, such as antibodies or DNA probes, that selectively binds to the target biological molecule. When the target molecule binds to the recognition element, it causes a change in the mass and magnetic properties of the magnetoelastic material, which can be detected as a change in the resonance frequency of the material.
Magnetoelastic biosensors have a high sensitivity and specificity because they can detect minor changes in the material's mass and magnetic characteristics induced by the binding of the target molecule. They're also simple and affordable to create, making them a promising technology for point-of-care diagnostics.
Magnetoelastic biosensors have been used to detect biological molecules such as DNA, proteins, and viruses in a wide range of samples including blood, saliva, and environmental samples. They've also been used to detect diseases in food and water.
However, there are several obstacles associated with the development and usage of magnetoelastic biosensors, such as the requirement for recognition element optimization and additional validation and standardization. Furthermore, detecting several targets at the same time is difficult in these biosensors.
In conclusion, magnetoelastic biosensors are a promising technique for high sensitivity and specificity detection of biological substances. Ongoing research and development will be required to optimize these technologies for various uses in healthcare, environmental monitoring, and food safety, enabling the development of reliable and accurate point-of-care diagnostic solutions.
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